Zaoqu Liu 刘灶渠

Zaoqu Liu刘灶渠

PI · Founder, πAI LabPI · πAI Lab 创始人

International Academy of Phronesis Medicine (Guangdong)广东智慧医学国际研究院

I am a Biomedical Multimodal Large Model Scientist at the International Academy of Phronesis Medicine (Guangdong), where I also serve as a Principal Investigator (PI). I founded πAI Lab to pursue autonomous scientific discovery.我现任广东智慧医学国际研究院生物医学多模态大模型科学家,担任课题组负责人(PI),并创立 πAI Lab,探索自主科学发现

My training spans clinical medicine, medical imaging, pathology, and bioinformatics. I completed my doctorate at Peking Union Medical College (Tsinghua University School of Medicine).我的学术训练涵盖临床医学、医学影像、病理学与生物信息学。我于北京协和医学院(清华大学医学院)完成博士学业

AI-ready Infrastructure and Autonomous DiscoveryAI-ready 基础设施与自主科学发现

Developing AI-ready scientific infrastructure and autonomous research agents that integrate knowledge, data, models, and tools to formulate, test, and refine scientific hypotheses构建 AI-ready 科学基础设施与自主研究智能体,整合知识、数据、模型与工具,贯通科学假设的提出、检验与迭代

AI Virtual Cells for Stromal Reprogramming面向基质重编程的 AI 虚拟细胞

Developing AI virtual cell models centered on cancer-associated fibroblasts to understand how fibroblast plasticity and microenvironmental interactions shape tumor ecosystems and to predict their responses to intervention以癌症相关成纤维细胞为核心构建 AI 虚拟细胞模型,研究细胞可塑性与微环境互作如何塑造肿瘤生态,并预测其对干预的响应

  • PathWeaver submitted to ICLR 2027PathWeaver 投稿至 ICLR 2027

    Our work explores how explicit reasoning graphs can enhance diagnostic reasoning in pathology vision-language models面向病理视觉语言模型,引入显式推理图,探索如何增强模型的诊断推理能力

  • OmniFigure submitted to ICLR 2027OmniFigure 投稿至 ICLR 2027

    We explore a unified representation for data visualization, aiming to describe different visualization forms within a common framework聚焦数据可视化的统一表征,探索不同可视化形式之间的共通表达

  • Founded πAI Lab创立 πAI Lab

    Advancing AI-ready scientific infrastructure and autonomous scientific discovery聚焦 AI-ready 科学基础设施与自主科学发现

  • Our study of fibroblast senescence appears online in Cancer Research成纤维细胞衰老与化疗耐药研究在线发表于 Cancer Research

    We investigate macrophage-induced senescence in cancer-associated fibroblasts and how their senescence-associated secretory phenotype contributes to chemoresistance in colorectal cancer研究巨噬细胞诱导的癌相关成纤维细胞衰老,以及衰老相关分泌表型如何参与结直肠癌化疗耐药

  • Joined the International Academy of Phronesis Medicine (Guangdong)加入广东智慧医学国际研究院

    Appointed as a Biomedical Multimodal Large Model Scientist, with responsibility as Principal Investigator for the multimodal biomedical AI agents research team任生物医学多模态大模型科学家,并作为课题组负责人(PI),负责生物医学多模态智能体研究

  • Our nasopharyngeal carcinoma study appears in Nature Cancer鼻咽癌多组学研究发表于 Nature Cancer

    We use multi-omic profiling to characterize nasopharyngeal carcinoma subtypes and investigate their relationships with response to induction chemotherapy通过多组学刻画鼻咽癌分子亚型,研究不同亚型与诱导化疗应答之间的关系

Selected work on multimodal learning, cancer biology and treatment response代表研究涵盖多模态学习、肿瘤生物学与治疗响应

12,187 citations H-index 52 Google Scholar · 11 Oct 2026被引 12,187 次 H 指数 52 Google Scholar · 2026 年 10 月 11 日

2026
Nature Genetics

Phenotype-driven discovery of intercellular signaling underlying complex trait variation at population scale

Co-first author共同第一作者 · Coming soon
Nature Immunology

Tumour-derived REG4 converts fibroblasts into antigen-presenting cells to overcome immunotherapy resistance

Last corresponding author最后通讯作者 · Coming soon
  • Tsinghua University School of Medicine
    Peking Union Medical College
    清华大学医学院
    北京协和医学院
    Doctorate in Medicine
    Pathology & Pathophysiology
    医学博士 · 病理学与病理生理学
    Advisor: Academician Fuchu He导师:贺福初院士
  • Zhengzhou University郑州大学Clinical Medicine
    Integrated Bachelor’s–Master’s Program (5+3)
    临床医学(5+3 一体化)· 本硕连读
    Master’s specialization: Medical Imaging and Nuclear Medicine
    The First Affiliated Hospital of Zhengzhou University
    硕士阶段:影像医学与核医学
    郑州大学第一附属医院
    Advisor: Xinwei Han, Zhongyuan Scholar导师:中原学者韩新巍

2026

  • World’s Top 2% Scientists (2023–2026, Single-Year Impact), Stanford全球前 2% 顶尖科学家(2023–2026,年度影响力),斯坦福大学

  • Outstanding Graduate of Beijing Higher Education Institutions北京市普通高等学校优秀毕业生

  • Outstanding Graduate, Peking Union Medical College北京协和医学院优秀毕业生

2025

  • π-HuB Rising Star Awardπ-HuB 明日之星奖

    AOHUPO / AOAPO / CNHUPOAOHUPO / AOAPO / CNHUPO 联合颁发

  • National Scholarships国家奖学金

    Ministry of Education · 2021, 2022, 2024, 2025教育部 · 2021、2022、2024、2025

2024

  • Early Career Fellowship, China Association for Science and Technology中国科协青年人才托举工程博士生专项计划

  • Henan Provincial Science and Technology Progress Award河南省科学技术进步奖

  • Rinstitute × iMeta Scholarship · Clinical MedicineRinstitute × iMeta 奖学金 · 临床医学

  • Outstanding Graduate Student, Peking Union Medical College北京协和医学院优秀研究生

    2023–20242023–2024

2023

  • Henan Provincial Award for Outstanding Scientific and Technological Papers河南省优秀科技论文成果奖

  • Outstanding Graduate (2023) & Merit Student (2022), Henan Province河南省优秀毕业生(2023)· 三好学生(2022)

  • Outstanding Graduate, Zhengzhou University郑州大学优秀毕业生

2022

  • Top Ten Graduate Students, Zhengzhou University郑州大学十佳研究生

    2021–20222021–2022

Wiley

  • Top Viewed Article — Cell Proliferation (2023)高阅读量论文 · Cell Proliferation(2023)

  • Open Science Excellent Author Program开放科学卓越作者

Research collaborations in AI and biomedicine科学智能与生物医学的研究合作

liuzaoqu@163.com