Drug sensitivity data (IC50 and AUC) for cancer cell lines from the Genomics of Drug Sensitivity in Cancer (GDSC) project.
Format
A data frame with 196,344 observations and 19 variables including:
- DRUG_ID
GDSC drug identifier
- DRUG_NAME
Drug name
- CELL_LINE_NAME
Cell line identifier
- COSMIC_ID
COSMIC cell line ID
- SANGER_MODEL_ID
Sanger model ID
- TCGA_DESC
TCGA cancer type classification
- DATASET
Dataset source
- COMPANY_ID
Company identifier
- NLME_RESULT_ID
NLME result ID
- NLME_CURVE_ID
NLME curve ID
- LN_IC50
Natural log of IC50
- AUC
Area under the dose-response curve
- RMSE
Root mean square error
- Z_SCORE
Z-score
- MAX_CONC
Maximum concentration tested
- MIN_CONC
Minimum concentration tested
- PUTATIVE_TARGET
Known drug target
- PATHWAY_NAME
Target pathway
- WEBRELEASE
Web release version