CellProgramMapper: Map Single Cells to Reference Gene Expression Programs

Maps single-cell RNA sequencing data to reference gene expression programs (GEPs) using non-negative matrix factorization. Enables cell type annotation and state characterization by projecting query cells onto pre-built or custom reference programs. Includes tools for building consensus references from multiple datasets. Inspired by and compatible with the Python starCAT package.

See also

Useful links:

• https://github.com/Zaoqu-Liu/CellProgramMapper

• https://zaoqu-liu.github.io/CellProgramMapper/

• Report bugs at https://github.com/Zaoqu-Liu/CellProgramMapper/issues

Author

Maintainer: Zaoqu Liu liuzaoqu@163.com (ORCID)

Other contributors:

• Dylan Kotliar (Original Python starCAT implementation) [contributor]